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| MCMP 61700 - Molecular Targets: Neuro Function And Dysfunction |
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Credit Hours: 2.00. The application of basic scientific principles from medicinal chemistry and molecular pharmacology, and new discoveries in biology, to the development of new drugs to treat psychiatric disorders and diseases of the central nervous system. Important examples of drug targets, and small molecules (either currently approved drugs or those under investigation) that target them, are discussed. Classes of drug target examples discussed include: G protein-coupled receptors, neurotransmitter transporter proteins, and ion channels. Processes of neurosecretion and neurodegenerative processes will also be discussed, as well as target validation and examples of the use of genetic models to identify CNS targets. Prerequisites: MCMP 57000. This course is offered even numbered years.
2.000 Credit hours Syllabus Available Levels: Undergraduate, Graduate, Professional Schedule Types: Lecture Offered By: College of Pharmacy Department: Medicinal Chem/Molecular Pharm May be offered at any of the following campuses: West Lafayette Learning Outcomes: 1. Understand completely modern approaches to assessing the nature and relevance of the various targets for CNS drugs and CNS drug discovery. 2. Demonstrate full comprehension and satisfactory presentation of CNS drug discovery findings from the current literature. 3. Demonstrate satisfactory critical evaluation of the primary literature. 4. Demonstrate a synthesis of knowledge acquired/demonstrated through the first three outcomes, to achieve a full understanding of a specific area of CNS drug discovery, and generate a satisfactory original research proposal in that area. Restrictions: Must be enrolled in one of the following Levels: Graduate |
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