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| BCHM 53600 - Biological And Structural Aspects Of Drug Design And Action |
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Associated Term:
Spring 2020
Learning Outcomes: 1. Understand and communicate the site and mechanism-of-action of a drug. 2. Understand and communicate the relationship between the pharmacologic mechanism and the therapeutic use of a drug. 3. Understand and communicate the scientific basis for the therapeutic use of a drug. 4. Predict, verbally or in writing, the biological response, if any, from a given chemical structure. 5. Understand and communicate the relationship between the structural features of a compound and the physicochemical properties that might influence biological response or the design of new agents. 6. Predict, verbally or in writing, the biochemical mechanism-of-action of a biologically active substrate or compound from its chemical structure. 7. Communicate and describe the relationship between the chemical structure of a biologically active compound and the receptor or active binding site, using enzyme or receptor models. 8. Predict, verbally or in writing, the biological response resulting from the chemical alteration or biochemical pathways. 9. Discuss the relationship between in vitro reaction mechanisms and the structural features that alter the in vivo biotransformation of a drug. 10. Understand and communicate the pathophysiologic processes associated with a particular disease state, and how they might be affected by drug therapy. Required Materials: Technical Requirements: |
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